Cold hands and feet caused by setbacks in blood flow to peripheral nerves or peripheral blood vessels. The main symptom is that the hands and feet feel cold in warm places as well as in cold places. Sometimes, you may feel cold in knees and you may also feel cold in various parts of the body, such as the lower abdomen and lower back. If the peripheral arteries are severely clogged, the blood cannot be supplied properly, which causes peripheral vascular occlusion (severe lower extremity ischemia) accompanied by tissue necrosis. It is characterized by the feature that the wound does not heal easily, and wounds appear on the inner walls of blood vessels, and the blood vessels are getting turbid due to increase in lime content.

When stem cells are injected into cold hands and feet caused by blood circulation disorders, the cells go where it is needed, and proliferates and differentiates in tune with the tissue of the damaged area, creating new blood vessels. Stem cells strengthen the walls of blood vessels, and thereby, helps the blood circulation made smoothly, enable the regeneration and proliferation of capillaries, and improve the circulation of the lymphatic system as well as the microvascular circulation. As a result, it is very effective for swelling and pain.